8-10 June 2022
CNR, sede centrale
Europe/Rome timezone

Nanoparticles meet Organized soft assemblies : Challenges and opportunities for the biomedical field

8 Jun 2022, 17:15
45m
Sala Convegni (CNR, sede centrale)

Sala Convegni

CNR, sede centrale

Piazzale Aldo Moro,7 - 00185, Roma, Italia.

Speaker

Debora Berti (Università degli studi di Firenze)

Description

The combination of inorganic nanoparticles (NPs) with organized natural or synthetic lipid assemblies has the potential to expand both our understanding and the applicative spectrum of these materials in the biomedical field.
This contribution will deal with hybrid systems composed of NPs and extracellular vesicles, (EVs). EVs are a major player in intercellular communication and mediate physiological and pathological processes. I will show how some central colloidal properties of EVs’ dispersions can be monitored leveraging the properties of NPs, by introducing a nanoplasmonic assay for fast purity checking and a plasmon-based nanoruler for collectively fingerprinting EVs based on their stiffness.

  1. Montis, C. et al. Nanoscale 6, 6452 (2014).
  2. Montis, C. et al. J Colloid Interf Sci 573, 204 (2020).
  3. Maiolo, D. et al. Anal Chem 87, 4168 (2015).
  4. Caselli, L. et al. Nanoscale Horizons 6, 543 (2021).

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