Speaker
Description
We will present some of our activity regarding the use of nanotechnology for exploring different aspects of biological sample preparation and their study of interest in medicine.
The presentation will span from the investigation and detection of several DNA intercalants [1], the generation of protein fibers and their structural studies [2], and last, TEM imaging of ion channels in cell membrane.
The presentation will further include the description and the use of an original scanning probe spectroscopy [3] that combines the simultaneous multiprobe excitation based on visible enhanced photon generation and hot electrons in order to obtain physical and chemical information on different kind of materials at nanometer scale.
[1] Nanomechanical DNA resonators for sensing and structural analysis of DNA-ligand complexes
S Stassi, M Marini, M Allione, S Lopatin, D Marson, E Laurini, S Pricl, ...E. Di Fabrizio
Nature communications 10 (1), 1-10, 2019
[2] A droplet reactor on a super-hydrophobic surface allows control and characterization of amyloid fibril growth
P Zhang, M Moretti, M Allione, Y Tian, J Ordonez-Loza, D Altamura, ...E. Di Fabrizio
Communications biology 3 (1), 1-13, 2020
[3] Hot-electron nanoscopy using adiabatic compression of surface plasmons
A Giugni, B Torre, A Toma, M Francardi, M Malerba, A Alabastri, ... E. Di Fabrizio
Nature nanotechnology 8 (11), 845-852, 2013"
